Is it necessary consume supplement with a glass of water?

[EugeneTheSage]

Certain supplements (in my case gingko biloba) are reccomended to take during the meal and with a glass of water, but I don't want to drink water during meal - the stomach juice gets dilluted and flushed down the intestine, because of that you have trouble digesting the food. I notice that I get sleepy when drinking during the meal or after the meal. Usually I drink 1,5hrs after the meal.

 

But if I don't drink water is there a possibility that cellulose capsules (in my case) wouldn't dillute? I guess it depends on food you eat. I guess taking supplements with a smoothie wouldn't be a problem, but what about taking it with buckwheat, oatmeal, mashed potatoes?

 

Or maybe I better take supplement 30mins before a meal with water? Of course it depends on the supplement, I am interested in gingko and bacopa which are reccomended to take during meal

[LSD-Rumi]

13 minutes ago, EugeneTheSage said:

But if I don't drink water is there a possibility that cellulose capsules (in my case) wouldn't dillute?

Beware, those capsules have tendency to get stuck in the esophegus if not taken with enough water. Someone I know developed a nasty ulcer in the esophegus from taking these capsules before sleep (not drinking enough water). 

At least eat some fruit after taking them.

Edited October 19, 2022 by LSD-Rumi

[Michael569]

It shouldn't matter in general. 

The capsule is often PH sensitive and will dissolve once it gets into the right place. Not all capsules are enterically coated to so some may dissolve in the stomach whether it is full or empty but that doesn't mean all nutrients are destroyed. 

All those components in Ginkgo and Bacopa have to first be broken down, absorbed, passed through the hepatic circulation and then, if you are lucky, a small portion of it (if it crosses the BBB) gets where you want it to get. Unless they just get used up elsewhere or get excreted before being re-absorbed. The pharmacokinetics of herbal products aren't as well understood or as well explored as those of medical drugs so it is best to experiment yourself and see where you feel the effect the most. 

Edited October 20, 2022 by Michael569

[EugeneTheSage]

On 10/19/2022 at 8:41 PM, LSD-Rumi said:

Beware, those capsules have tendency to get stuck in the esophegus if not taken with enough water. Someone I know developed a nasty ulcer in the esophegus from taking these capsules before sleep (not drinking enough water). 

At least eat some fruit after taking them.

Yeah, I notice they tend to stick to wet tissues