Has anyone tried both natural and synthetic 5-MEO-DMT?

[Jahmaine]

If so, is there any difference? 

[machii]

From my experience the synthetic is a more clean experience. Dosing is much more efficient. With bufo I have some wild bodily reactions. Moving around much. The comeup on bufo is also much more wild like being in the eye of a hurricane. With synthetic I'm pretty still and I slip in very gently into "the state". Synthetic also tends to be more colorful visually. 

Edited March 6, 2022 by machii

[Jahmaine]

31 minutes ago, machii said:

From my experience the synthetic is a more clean experience. Dosing is much more efficient. With bufo I have some wild bodily reactions. Moving around much. The comeup on bufo is also much more wild like being in the eye of a hurricane. With synthetic I'm pretty still and I slip in very gently into "the state". Synthetic also tends to be more colorful visually. 

Thanks for your response, that's quite interesting. Ive recently tried the natural version and was awestruck and all the rest of it, but I am curious of the synthetic version in comparison, some of the Seri people where they have the toad, feel that the natural one has the spirit of the toad in it and reckon it's more effective, although naturally I don't think they've actually tried the synthetic so was just curious at any comparisons out there.

[Vincent S]

From my experience, the toad venom is much more potent. Synthetic is much more manageable (at least when smoking)
I have never managed to pull it off plugging it, it requires ridiculous amounts to affect me.
But if you care for the safety of the frogs. I would say go for the synthetic. Both experiences are just as Beautiful.