NMN

[Farkhod]

Dear Leo and community,

What is your opinion about this nootropic supplement https://www.nmn.com/?

I wonder how come they jumped so quick after trial in mice to human, although there is only one clinical trial in Japan in 2019?

Thank you

[undeather]

3 hours ago, Farkhod said:

Dear Leo and community,

What is your opinion about this nootropic supplement https://www.nmn.com/?

I wonder how come they jumped so quick after trial in mice to human, although there is only one clinical trial in Japan in 2019?

Thank you

Research on NMN is highly inconclusive in a human model, thats everything you need to know at the moment.
There was a huge hype about this some time ago because Dr. David Sinclair promoted it on JRE among other podacsts. I personally dont have too many positive things to say about this guy, since he obviously cant even interpret data very well (some of his tweets just make me cringe). There is some preliminary data from animal studies that are high quality and reproducible - some of which show decent effects on aging and metabolism. I personally dont recommend it to my patients at the moment - just wait 2-3 more years for more human data! 

Edited January 29, 2022 by undeather