Ayahuasca after Bufo Alvarius?

[Javfly33]

I am looking to do a retreat of Bufo and I found a place close to where I live, they said though that they give ayahuasca after Bufo because it makes ayahuasca more powerful and to "treat the blockages that the Bufo session might have opened".

I don't have experience with Bufo so this would be my first time.  Should I do ayahuasca afterwards or maybe it would be too intense in a day and I should pass and just do Bufo? 

Edit: Its important to notice that I asked and they actually don't give the Toad but just straight 5-MeO-DMT (smoked)

Edited July 26, 2020 by Javfly33

[herghly]

I've done ayahuasca after 5meo and it has always been a good experience.

 

You will be fine

[mattslev]

From a safety perspective, you should be fine to do ayahuasca an hour after bufo/5-MeO, which will have been thoroughly metabolized. Whether having both experiences in one day is too much psychologically is entirely dependent on you. Trust your instinct.

Ingesting bufo/5-MeO after ayahuasca is where you need to exercise extreme caution due to the presence of MAOIs in the Banisteriopsis caapi vine, as that in combination with 5-MeO, which is a strong serotonin re-uptake inhibitor, can lead to serotonin syndrome. Potentially fatal. At a minimum, it is advised not to take 5-MeO for at least 24 hours after ayahuasca. Kambo is another medicine that can be lethal in combination with 5-MeO.

Article with great information about the pharmacology involved:

https://www.spiritpharmacist.com/blog/2020/6/13/a-tale-of-two-tryptamines-nn-dmt-and-5-meo-dmt-in-combination-with-maois

[Javfly33]

11 hours ago, mattslev said:

From a safety perspective, you should be fine to do ayahuasca an hour after bufo/5-MeO, which will have been thoroughly metabolized. Whether having both experiences in one day is too much psychologically is entirely dependent on you. Trust your instinct.

Ingesting bufo/5-MeO after ayahuasca is where you need to exercise extreme caution due to the presence of MAOIs in the Banisteriopsis caapi vine, as that in combination with 5-MeO, which is a strong serotonin re-uptake inhibitor, can lead to serotonin syndrome. Potentially fatal. At a minimum, it is advised not to take 5-MeO for at least 24 hours after ayahuasca. Kambo is another medicine that can be lethal in combination with 5-MeO.

Article with great information about the pharmacology involved:

https://www.spiritpharmacist.com/blog/2020/6/13/a-tale-of-two-tryptamines-nn-dmt-and-5-meo-dmt-in-combination-with-maois

thanks for the reply, that seems exactly the information i needed