If rectal administration is the best method 5 Meo DMT it should also work well with LSD.   I have already tried once 50 ug of 1P-LSD. The strength seems to be comparable to a 100 ug of ALD-52 (still not enough for ego death) or maybe a little bit less intense. Normally 1P is harsh, faster acting and a little bit stronger (100 ug of 1P is enough). Rectal 1P is very similar to oral ALD-52.   Other observations: - trip is smooth and pleasent. 1P taken orally makes me a little bit anxious - I have to mix it with small dose of ALD-52 - 1P taken orally cause CRAZY pupils dilitation. I have to keep my eyes nearly closed. I don't have that effect with rectal administration - trip duration seems to be shorter - rather six hours instead of twelve. Peak was quite intense for just 50 ug. I guess 75 could be enough to reach ego death. I hope I will be able to give it another try with a larger dose.