5-MeO-DMT, conciousness, brain, EEG coherence

[outlandish]

@Serotoninluv I only grasp that paper at a pretty coarse level, but this is fascinating stuff. Really amazing that there are measurable changes in the brain post-actute psilocybin treatment. The fact that this can be detected in brain imaging points out that seemingly subtle subjective experiences can have physical correlates. 

This idea of psilocybin triggering a DMN reset is very attractive. It certainly feels like that when you take psychedelics.

vmPFC-ilPC RSFC (ventromedial prefrontal cortex inferior lateral parietal cortex resting state functional connectivity, to the layman) does my head in lol. I'm glad you wrote your interpretation of the paper above, it helped me gather meaning from the read 

Really cool that this got published in Nature. It's also really cool that psilocybin can be effective in treating depression, it brings me joy that we live in a time when this is starting to be explored (again).

[tecladocasio]

On 20/02/2019 at 6:40 AM, Enlightenment said:

Ability to perfectly concentrate for 1h+ on any object in consciousness you choose, with no dullness/very high alertness, effortlessly

this is concentration , not meditation 

[Enlightenment]

@tecladocasio

42 minutes ago, tecladocasio said:

this is concentration , not meditation 

There are many definitions and meanings attached to the word meditation. Out of many different meditation techniques, this is actually the most popular, the hardest to master, the one that has the biggest impact on someones positive changes in the brain, the one that most conscious people on this planet have mastered, and the only one that leads to Nibbana.

On the list of techniques commonly called meditation, this one is actually the most fundamental meditation technique.

And concentration may be not the best word for it, because it's a training of both attention and awareness. In fact, it's impossible to achieve fully stable attention without greatly developed awareness and vice versa. 

[Forestluv]

@outlandish If you enjoyed that, check out this recent Cell paper on the effect of psychedelics on neurogenesis in cell culture. DMT and LSD are potent simulators of neural growth and neural plasticity (the ability to form new neural synapses and strengthen synapses). In particular, check out figs. 1A,B and 2A, I. Psychedelics are as potent as our own endogenous neurotrophic factor, BDNF. Dramatic and exciting stuff.

https://www.cell.com/cell-reports/pdf/S2211-1247(18)30755-1.pdf

[outlandish]

@Serotoninluv wow thank you for sharing that. I have so many comments/thoughts, but for now simply thanks!