Hey everyone. I have a quite specific question on 5-Meo-Dmt.
I am in my thirties and I have done meditation daily for 10 years including yearly retreats in a monastry. Despite this fact, I have started to suffer from panic attacks 2 years ago, but they disapeared very quickly after doing therapy and medication. (100mg Zoloft a day) For me, the panic attacks were a very physical appearance, I had big diguestion problems and was always loosing weight quickly, also no interest in food, and fear of death. I realized at the moment that the longterm meditation opened many parts of my deeper being, and there were fears that i haven´t been aware of, but seemed to be gates to pass on my way to the realisation of my true being - fear of death. fear of no excistance, fear of becoming insane. It´s the ego that struggles when it really comes to push it from it´s chair, and if it starts to feel that things become really real abiut your spiritual inquest, your ego isn´t sure of many things anymore. Somehow, the medication seems to balance it at the moment. I will go down on 50 soon, but it might be that I have to stay a year longer on it before i let it run out. I do my daily meditation and feeling very fine at the moment. In summer, i tried some DMT smoked and did a 100ug tab of acid, i had beautiful experiences, and even though it was NN DMT, i had a breakthough to meet this bright, undefinable formless presence (concidering it was NN DMT, this experience wasn´t feeling very physical, it was more like a mental journey, but still i could see how reality dissolves into one presence and unfolds, very beautiful when dualism of mind disappears). I paused the medication therefore for 8 weeks, but my symptoms were reaccuring after 3 months, so i decided to take the medication for another year.
I have been researching on interactions with psychedelics and Zoloft/Sertraline, and since the medication is a Serotonin reuptake inhibitor, it works on the 5-Ht1a and 5-Ht2a receptors, hinders the Serotonin to bind on the receptor and stay in the gap between your Receptors longer than normal so raise your Serotonin level. I already did NN Dmt on the medication, and it diminuishes the effects a bit, but still there is an experience. I researched a lot on the interactions of the medication and drugs, here is a nice overview from Tripsit:
https://wiki.tripsit.me/wiki/Drug_combinations
Basically, it comes to dangerous interactions when you have 2 substances that enhance the serotonin level in your brain. (5Htp, DXM, Mao Inhibitor/Ayuhasca, Tradamol, some RS chemicals can be very dangerous, there is no experiences on those...it will lead to a Serotonin Syndrome which can end deadly or with organs disfunctions) I now, Leo once wrote in a post "dont do SSRI and psychedelics, very dangerous - but i am sorry to say but this is a very undefined post that is not really true. (considering the fact that in Swiss there is many clinical studies on the use of psycedelics and for example depression with outstanding results, I even think that this new medicine will the THE breakthrough in about 20 years for curing mental so called "illness" but society doesn´t accept so far)
The "classic" psychedelics like (mushrooms, NN Dmt, LSD - the real LSD, no derivate) are due to my researched not physically dangerous if you are on a SSRI, of course depending on your mindset, psychodelics can stir up all kind of things out of your consciousness, leaving you being more confused than before or lifting your anxiety level a lot, therefore to be treated with lots of respect.
5-Meo Dmt seems to act stronger and different than NN Dmt, more physically, you see people shaking their body a lot and doing vibrant movements. It works slightly if induced orally, but still there is no proof or chemical sign that it contains MAO. Still the safest recommandation is "vaporazed" with low dosage on the beginning.
So here comes my question, it would be so nice to have qualified answered, since i have been screening the net for almost all reports of the last years, there is soo much stuff like : "yeah dude, stopp SSRI, they are shit" or "never do psychedelics when you have anxiety disorder, there is a reason you take medication" I hope receive some more specific answers, people who have experience about it or did some serious reseach as well. Maybe you can help me and other people, it could be very important. Or maybe you research a bit about it, Leo, you might have very good connections.
INTERACTION 5MEO (Vaporized) and SSRI - Experiences?
I think 5-meo DMT can show you how your deepest nature looks like, ald also show you how your mind tricks you and produces anxiety/thoughts/issues and so on. Therefor it could be very helpful as a medicine for people who suffer from their own worrying, anxiety and lead them to an experience where you normally block yourself from having, together with a therapist this could be amazing to work with.
And in fact i would love to experiment it, it´s very hard to resist and wait for another year or 2 to try it :-D
Thank you all so much, lets unfold this secret.