Michael569

not even with anabolic steroids. Without progressive, constant and repetitive mechanical pressure and micro-tearing that is impossible. You can maintain only as much as your body needs for basic level of functioning at the level of activity you're at (this is where the atrophy will eventually stop for anyone who cuts down on their exercise routine) but if you want to get a bit bigger, resistance training is the only way. For more functional strength, things like bouldering, swimming, sprints, primal movement etc are also useful. You won't get big but you can get very strong, agile and get immense core strength doing these things. But generally, with everything in the body - "you don't use it you lose it." It is a way of recycling resources and minimising energetic consumption to ensure survival and reproductive efficiency There is no need to have big muscles, in fact it becomes kinda counterproductive at some point but maintaining decent level of lean muscle mass with strong core and decent overall fitness level (rest bpm < 55-60) is a boost for your longevity and disease prevention goals

@fopylo sounds like your circadian rhytm may be out of alignment. If we push our sleep time too far, we may unconsciously reset out body clock even before it is time to sleep and so your body perceives morning even thou it is deep night. It take a little bit of work to put it back but this can help you get it where you need to get. https://www.amazon.co.uk/Circadian-Code-weight-supercharge-energy/dp/1785042017/ref=sr_1_1?crid=1K5FYGPI0ZP1W&keywords=circadian+code&qid=1646419459&sprefix=circadian+code%2Caps%2C129&sr=8-1 Quite enjoyable reading and I found Dr Panda's work fairly easy to follow. It is not too technical either.

Productivity Ninja by Graham Alcott Can't praise this book enough. As a chaotic qnd messy person myself this has been a tremendous help in starting to get organised. It will require some commitment to make the method work but it definitely works very well once it is in place. Books also talks about stress management, calendars, journals etc. Pretty much everything you need to create a single funnel system through which you will be able to organise tasks, meetings, projects and anything that life throws at you that neds to be categorised/postponed/attended/stored/filed etc. However I only see this book available on UK Amazon which may be a bummer depending on where you're based so perhaps there is another, equally awesome resource from a local author that would suit better

Don't focus on it too much. Mostly genetically driven as mentioned above. Focus on things you have control over in your life that are more important ?

Mechanisms are definitely interesting and they form a basis of hypotheses but most mechanisms eventually fail us. For example when it comes to FDA drug development, I believe less than 2% eventually make it through all trials starting from mechanisms. I love creating my own biochem pathway maps, like I have this huge drawing of cellular pathways that I made 2 years ago and its been fun making that and learning a lot but when it comes to human data, it should always take priority And in topics where we have a lot of human data (such as cardiovascular disease, saturated fats, cholesterol, oils) we should be looking at human outcomes with priority at all times because this is what clinical guidelines are based on which is also important for us, clinicians and practitioners to appreciate when working with real people. i.e. we should not be recommending or discouraging a particular cause of treatment simply with basis on in-vitro data because we "want it to work like that" if there are human outcomes that show "actually it doesn't work like that". The reason is one thing is observed mechanism in-vitro and one thing what is happening inside the human body. What if we have buffer systems negating the effects we see in the petri dish etc. True, there are confounding variables but we have ways to control for confounders through stratification and other techniques. Like you can literally tweak the statistics to ignore all but one confounder. Now I have no idea how to do that but it can be done by people who understand statistics. But then if something is appearing over and over and is a predominating occurrence in studies that involve hundreds of thousands of people, the odds of those effects happening by chance are gradually minimised. On the other hand where we have little human data, mechanisms are super important. yeah, this is a factor too. Pesticides, industrial processing etc. I guess ideally you want to be getting mechanically pressed EVOO form the best quality you can. My line of thinking was that , it appears that once people move away from sources of saturated fats towards PUFAs and MUFAs their health outcomes (be it CVD mortality, be it cancer, be it diabetes) are actually improving and the guy shows it beautiful in that article I shared. And for most people the % of calories coming from PUFAs and MUFAs even at the segments of highest consumption are still negligible to have a huge impact it appears. But I continuing to explore this topic deeper as it is super important and I don't feel confident with my interpretation of the data just yet. For now I believe reduction of SFA and increase of MUFA & PUFA is a better idea than the other way around. Also, you could play this game by sharing a video of farmed animals, the way cows are treated and impregnated, the way chickens are walking and eating each other feces or the way animals ar being castrated and slaughtered.. And I don't want to go into ethics but if you can make it through Earthlings without shedding a tear or covering your eyes at least 10 times ....

Most of it comes from algae so why not go straight for the source and get some Algal Oil ? more ethical/ more sustainable and prices are more and more comparable with fish oil

Seems the boys were holding back until Leo commented ?

If your circadian rhythm is aligned with the cycle of the day, it is normal to start getting sleepy with loss of natural light....well in ideal world at least where there is no blue light and never-ending screen time. It would be considered normal to start feeling that sleepiness about 2 hours before your typical bedtime and that feeling should gradually increase if you don't expose yourself to stimulants or excessive amount of blue light. You shouldn't feel sleepy during the day although it is normal to feel tired after an exhaustive mental or physical work ) or sex) It is not normal to feel sleepy after food and it is not normal to feel sleepy and low in the morning other than the buffer time it takes to fully wake up. Also for a healthy young person, one should not feel tired at random points of the day if there was no previous exhaustive task. Some people nap in the afternoon but if the reason for nap is that one is completely shattered by lunch meal then something needs to change (often it is the meal consistency especially the amount of processed carbohydrates and low fibre content). A meal should be energising not sedating

Let's try to be tolerant & inclusive of other people's opinions and worldviews even when they collide with our own. Thanks!

Few questions: What is your diet like? Frequency, meal, any dietary restrictions etc Do you have any ongoing health conditions? Have you ha dany infections in past 12 months? Have you changed your environment / jobs? Any personal trauma, bereavement, stressor that came up? Have you tested covid19 positive in past 12 months? Have you been put on high doses of antibiotics? Do you take any regular medication? What is your sleep like? Do you exercise? How often? Have you had your vitamin D levels measured? What were the levels? Have you had your iron panel (ferritin, transferring TIBC etc) measured? What were the leavekl Have you had your blood cells measured (leukocytes etc)_ How is your digestive health?

@Average Investor thanks for comms! @John Paul it is a good idea to start with your doctor and try to find out what is actually going on. Get either a diagnosis or at least some leads to what might be going on. We actually have a super knowledgeable specialist (GIT medical doctor) on the forum @undeather who may provide way more info about where to start and what to do with the results. I do work with guys who have gastrointestinal difficulties as well but am not a doctor so can't diagnose you or run any sort of blood tests or stool tests so definitely pay a visit to your MD and consider getting some basic checkup.

@Austinsmith depends on your baseline diet your needs and your goals. Ideally you want to be reliant on as few as possible with the exclusion when one is following a diet that does not contain particular nutrients or taking supplements for a restricted amount of time for a therapeutic purpose (3-6 months usually)

https://youtu.be/litXW91UauE

start by fixing this. Bulk up the fiber content of your meals to at least 50 grams of fibre per day if you intend to maintain decent health beyond 30s. go by your urine colour. If your kidneys & liver are otherwise healthy,you want to see the urine kinda bright, like a diluted white wine. If it gets too dark or too smelly, drink more. I'd suggest grabbing some nutrition books and educating yourself about how to create a healthy diet that goes beyond a bunch of protein. A complete wholefood diet will provide majority of your protein needs (and that brain fog would probably disappear pretty quickly). Lots of videos how to do that available too. You want a healthy balanced based mainly around plants with a little bit of animal foods if you are concerned about good health maintenance. Animal heavy diet is good for gains but may not be the best for the other goals.

if this is the only concern, then you may find that there are other non-meat sources you could eat. The question is "would eating meat trigger some sort of internal ethical conflict in you?" If not, you can probably experiment with it and see how you feel. If that is the way, then I'd try to get it from high quality sources, grass fed, organically fed, ideally through some sort of organic certified way. If the answer is "yes, it might trigger a conflict" (meaning every time you eat meat a part of you is screaming in guilt and frustration) then I would look into other denser plant sources first , such as tempeh, tofu and eating more legumes, especially red and green lentils as well as Indian dahls which are just LOADED with protein.

Experimenting with vegan protein shakes may actually be a quick win here. Lot of people react poorly to concentrated dairy. If it doesn't help look further. I would always put your long term health ahead of protein requirements and short term gains and IMO relying on heavy protein from dairy sources is burning candle from both ends. There are other good sources out there too Those wrinkles could simply be sign of some deficiencies such as fatty acids, dehydration, excessive sun exposure, genetics (some people just naturally age faster) but could also be a side product of pushing that cellular cycle too much by eating too much, dosing too much protein and just stimulating the body too much. Also potentially toxin exposure in the environment could be an ageing factor if you live in hyper polluted area

good stuff, Andrew Huberman went deep into this in one on his "optimise your workspace" podcasts. Definitely worth watching. Been a while since I got so much value from a single video.

couldn't agree more (and with everything else @Loba said). Sometimes what we would label as "neurotic" or "messy" or whatever name you put on it is just a child screaming inside of us that needs soothing, love and that needs to be cared for.

didn't read your first response so no hard feelings I'm trying to work on creating a separation between my dietary beliefs and my identity so that I get triggered less by counter-opinions (but I got a lot of work on that :D) . Food for thought perhaps? Btw I have not done in-depth review of the literature on seed oils, CVD & saturated fats because I don't think I have enough statistical knowledge to interpret those results without a huge degree of bias. Maybe you do? However let me refer you to the top of the expert channel I have found on this topic so far. I'm gonna have a look at the links you listed but for some proper brainfuckery consider watching this. al This guy has convinced me that mechanisms are not everything and that we actually need to look at the human data instead. And for even more depth, consider reading this too. This is the proper nerd stuff https://www.the-nutrivore.com/post/a-comprehensive-rebuttal-to-seed-oil-sophistry If you read & watch both and still remain unconvinced then you must be in denial. I was too for a very very long time. btw on those two links you sent: 1. I will review that meta analyses study in depth - looks interesting 2. the second link is one-person case study with mechanical speculation - case studies are at the very bottom of pyramid of evidence-based hierarchy. We cannot extrapolate claims based on case studies, they form potential suggestions for future research but on their own case studies are more just "interesting" rather than being extremely valid or reliable for an evidence-based approach. Btw this is on eggs, I don't have a thing against eggs although eating as many as this guy isn't probably a good idea for majority of people despite one guy being able to get away with it. Also, I no longer think that cholesterol in the diet necessarily causes heart disease, the mechanism is probably more complex than that and more tied to the saturation index of the fatty acids The sources Iisted above will be based on highest level human data evidence.

I agree with this. Once you lose a certain colony of bacteria, it may take you decades (if ever) to get them back. Some of these colonies have been with you since you were born and that moment you have sampled the vaginal bacteria on your way "out" , they were the very first that colonised your sterile infant gut. Ofcourse for people born through C-section and bottle-fed this diversity may be completely different. Also the issue is that once you lose them to the overgrowth of protein-digesting species that are generally more pro-inflammatory, I have no idea how easy is it to get that balance back. Those "free" spaces in the intestines will now be taken by species that were not supposed to be overpopulated and that can create completely new immune challenges such as depletion of intestinal mucous and increased proximity between the bacteria and the walls of the gut (without the mucouse to keep them out) which may result into massive flare-up of autoimmunity (in theory at least) and separation of tight junctions of the intestinal walls (in theory at least) I don't think we know as much as we could about the complexities of the microbiota and even if you read about the work of experts like Sonnenburgs, this is what they will tell you. "we simply don't know enough to risk losing it ". I actually contacted Erica Sonnenburg, the co-author of the Good Gut and asked her about the ability to restore lost populations in the gut but never heard back.....but I would have been surprised if she replied to be honest

I used to think this too but actually, people who consume more linolenic acid (main constituent of the vegetable fats) have overall better health. WHen you look at the long term data none of the theories against vegetable oils stand their ground and all fall to pieces whether it is AMD, cancer, diabetes, fatty liver disease or heart disease. Vegetable oils have not yet been proven to cause disease. It seems that the main reason why this is is the extreme content of antioxidants which cannot be said about shit food like butter and lard which is like consuming cyanide The only exception is when they contribute to obesity in excessive consumption which in itself is a risk factor for all cause mortality but in moderate consumption, vegetable oils are actually useful. But then anything eaten in moderation which would contribute to becoming obese is a risk factor for disease because it is no longer about the food but about destroying one's metabolic efficiency by carrying all that adipose tissue

Thank you for raising this thread! It is easy to forget that we are all here because of the man's dedication, commitment and love. Leo has changed the trajectory of my life 360 degrees and I am 1000 fold happier than I was 4 years ago having turned interest into a passion and into a profession. Thank you Leo! Your work has changed more people than you will ever know even thou in our arrogance many of us like to forget that.

^^ IMO jumping on aggressive chelation protocol without having done a proper clean-up and lifestyle optimisation for at least 6 months is like jumping in a whirlpool without ever bothering to learn to swim and hold one's breath at least 2 minutes.

Yeah, I do. If you are healthy and don't have any digestive issues with them I don't see a problem with eating as many fruits as you can, ideally whole and unprocessed. About the sugar topic? Well, there are several types of sugars. Complex sugars are digested slower (yes, this is a belief, I haven't measured this myself in a lab) than simple sugars such as orange juice. I'd preferably eat that orange whole but it is not a big deal in general.

@Yali I can't comment on that without tapping into my "beliefs" so I'll just say, stick to what makes you happy and what makes you feel good