Michael569

Omg i forgot about this one, let's bring it back to life you all beautiful people

@Yimpa yeah, always

@Yimpa thanks i do every now and then when i have something to contribute

Notion or Obsidian for organizing. Plus the book Productivity Ninja by Graham Alcot to get you started on creating a filing system

@Buck Edwards glad it resonated

Maybe true but how is this helping you build a success. It just sounds soooo....disempowering? You can run mental gymnatics on free will and determinism but the question is, "will it put bread on your table and feed your kids"? Its no wonder so many guys on this forum are stuck on armchair philosophy while unable to find a girl, a job and move on. There is an order to priorities in life and sometimes the success (whatever that constitutes) comes before chasing the ultimate truth. Practicing spirituality should not prevent you from pursuing success and success does not automatically mean abandoning your integrity and values. Success can mean having a decent career, regular income, a family, stable finances having your life in order and not lacking in the major areas that constitute a balanced life. Success doesn't have to mean swimming in cash, owning 10 houses and driving a Lambo, I'd say that's the opposite of success even, that's just a childish hedonism. So if you can achieve a life that you'll be proud of and help you die with a smile on your face while not completely sacrificing your soul....then that's the success you can pursue without getting yourself stuck on an armchair philosophy.

@RendHeaven true. Placenta does protect from a lot of things but certainly possible that epigenetic changes could happen in utero due to exposure of foreign substances leading to over or under-expression for different proteins coding for parts of the immune system like T-regs or CD4+ cells which are responsible for immune tolerance (among many other things). @PurpleTree couldn't tell you, depends from one person to another and depends on the particular diagnosed condition. I'd see supplements as an extra 2% bonus on the top of major lifestyle/dietary protocols that need to happen first. On their own most supplements are quite weak in the absence of more holistic approach With an autoimmune disease, for example, I'm immediately looking for existence of habits that need to be corrected (drinking, smoking, vaping, poor diet, late sleep times, physical passivity, lack of down time etc). I'm looking at the diet - antioxidant intake, sodium intake, nutritional deficiencies, fibre intake (in some fibre is contraindicated tho) excessive intake of foods associated with worsening of symptoms (of that particular disease with respect to existing evidence), polyphenol intake (at least those where we have some decent evidence of efficacy) etc. We're looking at environmental exposure - heavy metals, microplastics, water , air pollution, daily exposure to chemicals...we also try to explore environmental exposure across lifetime but that tends to be difficult to do becaue we rely heavily on individual recollection. We'd also want to explore family health history where possible and where known and as far back as we can. And as a cherry on the top of that, we might add a few supplements with existing data or where efficacy is speculative/experimental (I usually try to let the person know whether evidence exists and what quality is available). Some people are open to experimentation and some don't want to take risks so again, person to person differences

Message me if you wanna chat about it, I'd prefer not to go into it all publicly.

Its a huge topic with tons of good research and yet I don't think we fully know what is the exact cause of the loss of immune "self"-tolerance and initiation of self-attack. We've got plenty of good evidence pointing towards genetics, environmental toxins, major deficiencies, microbiome disruptions, diet, lifestyle, chronic inflammation, mis-diagnosis, untreated allergies, intolerances, gut permeability etc. If you get diagnosed early on in life, it is most likely genetics only. For people who get diagnosed late in life, there was probably a strong lifestyle factor involved but usually you're completely unaware until the first flareup We know mechanistically what is happening for example in Coeliac and can pinpoint it to a cascade of molecules that trigger the self-attack but we don't yet know the "why" although we can see genetic susceptibility being a critical factor of excessive gliadin binding to the antigen-presenting immune cells. Other like MS or Lupus seem to be heavily linked to toxin exposure in early life as well as vitamin D deficiencies (among other things) but also heavily rely on genetic susceptibility Each of those conditions has very unique aetiology, very specific mechanisms but there are also many similarities you can observe. They are really tough conditions for the people who experience them. The drugs used are strong and have lots of side effects and people often go through flare ups and remissions over and over. It can be pretty depressing, yeah. Full remissions does sometime happen so in some people autoimmunity is very manageable (I'm trying to avoid the word "curable on purpose because there is a lifelong susceptibility in those who've had first attack) but it depends on many things. In my practice I've seen two interesting cases of symptom remission, one with MS, the other with ankylosing spondylitis, both seemed to have been triggered by a combination of lifestyle & toxin exposure (both were smokers), both were stressed a lot and both had disrupted sleep pattern (and probably genetics) but both seemed to have got better with lifestyle optimisation and diet improvement + lots of supplements, some herbs. . Its been years now and both seem relatively stable the last time I checked (i like checking on old clients every now and then) so there are options available to people.

I haven't really had much alcohol over last decade but in the past ( teens and early 20s) I'd say at least 6-8 shots to get into the proper mood without blackouts. These days if I have more than 1 beer I'll feel it a bit so maybe the tolerance goes down with age especially if you're someone who doesn't drink at all. Its not like you're missing out on anything although funny enough my wife and I got together and started dating when we were both a bit tipsy, 14 years ago, so it did help to break the ice eventually

You got drunk on 1 litre of cider? 😄😄

I wonder what % of global AI horsepower is being used to cater to horny men or answer questions by men about sex

I can't speak for the wider community so will selfishly say what would be a starting point for me: New emergence of human evidence from sufficiently controlled randomized trials that suggests harmful effects of PUFA -rich oil consumption in any domain associated with chronic health disease (heart disease, diabetes, cancer, musculoskeletal disease , autoimmunity, mental health, neurodegenerative disease etc) Pre-requisites reasonably controlled environment (challenging but not impossible) healthy population and population with ongoing health condition both (separate trials) controlled for total calories (all groups consume roughly similar calories to avoid) reasonable participant blinding (people wouldn't know what's being tested and who's consuming what oils - this would be hard to do but not impossible) controlled for weight loss / weight gain decent randomisation to allow mix of different genotypes, bodytypes, etc properly assessed at day 0 (whatever you're measuring, you measure before and after (would be cool) all oils used derived from mechanical means vs from non-mechanical means (potential ethical consideration if this presumed harmful effect of refined oils) Multiple such trials would be sufficient reason for me to start reconsidering my position especially if someone could meta analyse them into existing data and notice the "needle" of risk ratios moving now. fair point! how does the above sound?

There is many ways to look at this. I don't know how old you are so maybe lot of this doesn't apply to you yet but in general, age, is a strong determinant for what women want. [Note: the age brackets are arbitrary often. Some women are incredibly mature and responsible in 21 and some are childish and immature in 35 so take the below with a pinch of salt] Younger girls, under 26-30 (unless exceptionally mature for their age) tend to go for looks, charisma, style of clothing, hair, money, cool cars, cool boy status among guys and girls etc. More superficial, more short term oriented. After 26-30, lot of girls mature up emotionally and may now be looking long term. They've done their share of dating, had some fun with the cool guys and many are now thinking about a potential long term boyfriend, even husband and father for their kids. New criteria are now introduced into the equation: ↓↓↓ looks - looks still matter but not as much as they did before. Proper grooming, washing and all of that is absolutely necessary but don't get obsessed about it. There are now more important things in play. competence - do you have a job? Are you relatively educated? Do you look like you're advancing through some sort of career and can provide for her if she gets pregnant with you? Can you do basic housework around the home. Can you cook at least 10-20 meals? Do you consider certain duties "woman's jobs" or can you seamlessly run the entire household yourself if needed? Are you relatively handy? (nothing crazy but basic things like building ikea furniture, unclogging toilet, changing vacum cleaner filter etc) confidence - not a cocky teenager's fake confidence but an actual confidence stemming from experience and expertise. Can you take over and make strategic decisions for you guys when necessary? Can you then stand behind those decisions? Are you able to stand your ground when challenged by other men or when men are hitting on your girl? Are you jealous and insecure a lot? DO you tend to hit on other women? Do you get defensive if she teases you or pokes you into your weak spots? (metaphorically) Do you have unresolved mommy issues? Are you too clingy, touchy-feely? Humour - are you fun to be around (you don't always have to be), can you crack jokes, can you make her laugh, can you make fun of yourself and be ok when she teases you? Can you help lift her mood when shes upset. care - are you empathetic? Do you exert fatherly qualities? Do you actually care about her or is she just there along the ride and you don't care if she leaves? Do you want kids? Could you care for a kid? Can you take care of yourself properly or do you need a woman for that (mother or a girlfriend) passions & interest - do you have something you're passionate about and that will sustain your mental health and purpose across life? Do you read? Do you have interesting hobbies? Or will she have to nurse you like a little boy who doesnt know what he wants in life? (men without purpose are more likely to end up depressed later in life) health - Are you healthy? Are you taking care of yourself? A mature intelligent woman will be severely deterred by health neglect, major unresolved health issues (obesity, dental problems, frailty, alcoholism, addictions etc). Are you fit enough to be able to protect her or your child if needed? Will you be able to wake up 6 times a night when you have a toddler and still function Sexual health - Can you get hard properly in the bed? Can you give her orgasms? Are you grossed out by oral sex? Do you ejaculate prematurely often? Do you have poor genital hygiene? Do you have some weird sexual kink? life strategy - do you have a plan for your life as you enter 40s, 50s, 60s. Are you thinking about retirement, finances, housing. Do you want to get married? Do you want to have kids? Are you saving already for your first home or are you pissing it all away on garbage? Obviously lot of this won't be obvious on the first date but I assume you're talking about mature relationship that goes beyond casual shag with a tinder girl. If you do, the above list can get you some ideas for what could be desirable for women. I might be wrong on many of these points so would be curious for ladies to comment more

@Davino do you find it changes according to the composition of your meals? Sometimes if, for example there are too many high GL (glycemic load) carbs and not enough protein and fibre to help slow down the gloucose absortion it can influence your post prandial energy. I've definitely been experiencing that in the past before I started looking into health. Aside from that, if it persists I assume you're a healthy and fit dude but if concerned you could have your fasting and post prandial glucose levels checked?