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I’m interested in information on the SC (subcutaneous) ROA (route of administration) for psychedelic compounds. Namely, 5-MeO-DMT and DPT. Following the advice of @What Am I and @bambi as well as my own research, I have a decent understanding of sanitary preparation methods, risks involved as well as injection technique. I’m reaching out here to see if anyone has two cents to add on a couple main questions I have as I’d like to broaden my scope of research. I’ll list them below: 1) How does one determine the eligibility of a chemical for this ROA? If fat-solubility is key, how does one determine the fat-solubility of a chemical? Is this something that can be determined from chemical datasheets alone? 2) If a chemical is well tolerated via IM (intramuscular injection), is it assumed to also be so for SC? If answering, please provide sources so I may pursue them in my research. For @bambi and @What Am I directly, could you two please provide information sources that lead you to using SC over other ROAs? Given the stigma associated with needles, I am sure there must have been a good amount of research pooled before jumping in. Thank you all! If this post breaks any rules, admins, please let me know so I can correct it.
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@What Am I Thank you so much for the info! Your experience and input is invaluable. How would you describe the difference in breakthrough experience with subcutaneous injection vs vaporization? Do you experience it for a longer duration? I have no experience with either, but am fascinated by what I read.
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@What Am I @bambi What’s your experience with subcutaneous dosages? What do your dose ranges look like? Gauging from my research into IM and SQ 5-MeO-DMT, it seems like for most people: low doses are between 2-5mg, medium doses are between 5-8mg, and breakthrough doses are between 8-20mg. Given information is scarce on this, and you both have experience with it, it would be great to get your inputs! Is this any bit accurate? Obviously knowing mg/kg body weight would be ideal! Also, if y’all have experience with SQ DPT, I’d be curious to know your dose ranges on that as well!
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Thank you for the speedy response. It was indeed scouring through your (and bambi’s) post history that I became curious about this ROA. It is seldom talked about despite seeming to be fantastic in terms of dose measurement, repeatability and relative safety and simplicity. Hence my quest to learn more. I will wait for others to chime in, as hopefully someone can guide me to a greater understanding. I would love to understand the mechanisms for determining positive eligibility for SC injections. I take your word that it is a safe assumption that IM and SC are more-or-less interchangeable as ROAs, but I would love to know why. These things are fascinating! Many thanks again for your response! If I find considerable reputable sources, I will post them to this thread for others on a similar path of understanding.