I find it very hard to name the most empowering video, or even a top ten! But I think what have opened my eyes most are his videos about not caring about what people think of you, being more confident and being positive.
I feel like I've made some progress over these areas and have been noticing how negative the world is that were all living in (Generalization, yes). But yeah I have to say that his videos in general could help alot of people, only if they would become mainstream. Right now not a lot of people in our society really "study" this or even want to understand it or if they do they do it behind closed doors.