Those of you interested in exploring B vitamins be sure to try methylated forms of B, as well as TMG (trimethylglycine), if you struggle with chronic fatigue, digestion issues, and brain fog. There is a common genetic mutation called MTHFR, which means your body cannot process B vitamins without the correct form of B vitamins. I personally have the MTHFR gene. Anyone can test for it, as well as other genetic mutations which may likely be the bane of your health issues. I use a brand called AOR B complex or ATP Lab Methyl SynerB. Both are great. The difference in my energy, clarity, wellbeing and ability to heal (I'm an athlete) was night/day after taking methylated B vitamins. Both creatine and glycine help as well in the methylation cycle.