I find this thread enlightening, even as a well dosed child of the 60's. There seems to be a general conception that we are all pretty much the same and people tend to believe their own experiences are just how it is. Then they are puzzled that their trip is so different from others or maybe doesn't even work. I'm no different. It has taken me some years to finally figure out that regular DMT doesn't work as well with my brain. I did Ayahuasca in the Amazon 4 times over a couple week period and did get high but few visuals and certainly not what I hear about. The last trip was led by an indian shaman (the artist Pablo Amaringo) who certainly brought something more to the table, but still I wasn't in that magical world. Some years later I did some locally with people working a Brazilian tradition. I told the leader that I didn't get off that well in the past and on the second dose he gave me a rather large cup. The result was a tremendous sense of anxiety but I was still very much in the canyons of Los Angeles. I have also smoked DMT many times and I get a bit of a mushroom vibe but that's all. LSD I still love as I just melt into mystical love and light. Mushrooms are not so mystical and often there is anxious hell to pay coming on. 5MEO I am just trying. First about 5mg and I liked it. Then I tried 20 but with my inept smoking technique I think I got more like 10 or 12 but it is straight up and love love love. I am looking forward to 25mg but a sitter is in order and I haven't worked that out. Anyway you work with what you have. BTW I used to go for large dose LSD trips, tying to duplicate previous religious experiences but I eventually figured out that it isn't the size the matters lol. In fact if I get too high it is more difficult to bring value back. BTW I haven't given up on DMT and am considering exploring changa as it gets rave reviews and is supposedly easier to dose. And thanks so much Leo for your intelligence, hard work and courage. I am sure you have gotten a lot of flack for going down this path but the truth is the truth even if it's hard to swallow and has to be taken rectally.